I haven't seen papers on in vivo responses of rats to
superantigens, but here are three papers on the in vitro
responses. They are confusing, because some workers find
that SEB causes strong proliferation of rat T cells, while
others find weak stimulation and call SEB a
"supersuppressogen" (in certain circumstances).
Sellins, et al., Eur. J. Immunol. 22:1931 (1992)
Ben-Nun, Eur. J. Immunol. 21:815 (1991)
Herrmann, et al. J. Immunol. 152:4300 (1994).
The Herrmann paper cites a paper by Gold et al. (J. Exp.
Med. 179:63, 1994) about clonal deletion of rat T cells
differentiating in rat-mouse chimeras.
Jack Komisar
