IUBio

anti-rat T-cell V-beta antibodies

Phil Shields pshields at microb.adelaide.edu.au
Tue May 30 21:01:38 EST 1995


Dear colleagues,

I have recently read a paper:

      Terres-Nagel NE, Herrmann T, Gold DP & Hunig T (1993) Analysis of the   
    rat TCR reprertoire and superantigen reactivity with TCR V-specific       
Ab's. Transplant. Proc 25(5):2778-2779] 

that describes the use of anti rat TCR V-beta specific antibodies (anti-Vb-8.2 
[R78]; anti-Vb-8.5 [B73]; anti-Vb-10 [G101]).

I was wondering if 
(i)  anybody out their knows how I could get hold of these antibodies [or 
hybridomas], or if they could give me an Email/fax/address of one of the 
authors involved in the aforementioned paper.
(ii)  also does anyone know if these Abs are stimulatory, anergy inducing or 
deleterious in vivo?
(iii)  Could someone please fax me one or all of these three papers cited in 
the Ref's of the aforementioned paper. I do not have access to these journals.

	- Kampinga J, Kroese FGM, Pol GH et al: Int Immunol 1:289, 1989.
	- Torres-Nagel NE, Gold DP, Hunig T: Identification of rat Tcrb-V8.2, 
8.5, and 10 gene products by monoclonal antibodies. Immunogenetics 37:305, 
1993.
	- Herrmann T, Torres-Nagel NE, Huber B et al: (submitted for 
publication before Oct 1993 ?)

My interest lies in rat models of autoimmune diseases and the involvment of T 
cells in pathogenesis of autoimmunity.

Thank-you very much.


Philip Shields
Fax: (Australia) 08 303 4362
Email: pshields at pene.science.adelaide.edu.au

Dept of Microbiology and Immunology
University of Adelaide,
Adelaide, Sth. Australia, 5005



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