Must be before 1980 at least...the multicluster plate was in use in the
late 1970s in immunology labs for sure. The originals were 6-well and
12-well...perhaps at the beginning of monoclonal antibody technologies.
I do know that the µtiter plate was around in 1980 when Eva Engvall
invented the ELISA. Perhaps she knows the answer. You can reach her at
the LaJolla Cancer Research Foundation in California:
eengvall at ljcrf.edu.
