IUBio

CTL vs transfectant made in mouse cells

Mike Whelan whelan at bbsrc.ac.uk
Fri Nov 24 11:06:21 EST 1995


dtyyu at ucla.edu (David Tak Yan Yu) wrote:

>I have put a human HLA class I gene into a mouse cell line.  I would like to 
>test if human CT can be generarted in my patients towards this transfectant 
>with restriction at the transfected HLA class I protein.  
>¢Ò¢é¢þ

If it's any help we have done a similar thing with bovine and equine
MHC transfected into mouse L-cells and yes, you do get killling so I
can't really see a problem. Perhaps you might like to tell us more?
Regards
Mike Whelan




More information about the Immuno mailing list

Send comments to us at biosci-help [At] net.bio.net