IUBio

Signal transduction by ClassI MHC

brett brett at BORCIM.WUSTL.EDU
Fri Sep 22 13:14:12 EST 1995


>I was wondering if any research has been done on whether or not the 50
>kilodalton cytoplasmic domain of the class I MHC plays a role in signal
>transduction. If so, what is the outcome of the signal?
>
>Just interested...anyone got any ideas?
>
>-Janet

I seem to recall that the alpha chain can be phosphorylated upon cross-linkage
at the surface, but no refs at hand. check medline.



Brett Lindenbach
    
Program in Immunology                              
Washington University - St Louis                  
brett at borcim.wustl.edu                             

"I own my own pet virus. I get to pet and name her." - Cobain




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