I will give the simplistic answers you can read about the details and
caveats:
Please no flaming my brevity...
>In a "one way" MLC you measure the proliferative respons of responder
cells to
>stimulatory cells.
>But exactly which cells is it that are proliferating?
T cells
>And which type of cells are the stimulating cells?
APCs primarily Dendritics
>Are the responder cells memory T cells or the naive T cells (or both).
Probably both
In the
>latter case they would require
>a co-stimulatory signal (B7) which I suppose they could get from the
stimulator MO and/or
>dendritic cells.
>
you got it....
>Best regards
>Jes Dietrich
