You should have little problem freezing a monoclonal. I suggest you
freeze it below -50 C. Also, be sure that the clone is not an IgG3 or
IgM. If so, you may have some problems.
birman at lnf.cnrs-mrs.fr (Serge Birman) wrote:
>Dear Netters,
>I just purchased a monoclonal antibody. This Mab is shipped lyophilized
>and the company recommends to dissolve it in water and keep in the
>fridge. However, for longer storage, I would like to store it in
>aliquots in the freezer. Is that possible without losing too much
>activity? Which buffer should I use? With or without glycerol? I was
>wondering whether glycerol can be harmful to some antibody.
>Thanks in advance for your advice.
> Serge
>birman at lnf.cnrs-mrs.fr
Bryan Kiehl
GenBio
GenBio at msn.com
San Diego, CA
