IUBio

Parkinsons-Pesticides

Tim McNamara timmcn at minn.net
Fri Nov 15 21:49:07 EST 1996


In article <328C735E.651D at icanect.net>, werner42 at icanect.net wrote:

>Does anyone have information on reseach done connecting Parkinsons
>Disease to persons having been subjected to heavy doses of pesticides
>over prolonged period of time?

Parkinson's is a specific degenerative neurological disease which appears
to be largely a genetically-influenced illness affecting the substantia
nigra and possibly diffusely throughout other brain structures.  The
clinical symptoms of Parkinson's (e.g., resting tremor, cogwheeling,
bradykinesia, postural changes, etc) can be mimiced by other conditions
such as progressive supranuclear palsy, olivopontocerebellar degeneration,
etc.  I would imagine that any substance with neurotoxic potential could
produce such symptoms but would not induce true Parkinson's.  The
"pseudo-Parkinson's" syndrome associated with neuroleptic medications
would be one example.  I would not be surprised to learn of similar
effects from other chemical substances such as pesticides.

I'd recommend a Web or WAIS search for sites related to keywords such as
neurotoxins, Parkinson's, movement disorders, etc.

Good luck!

Tim

-- 
The wheel is turnin' and you can't slow it down,
you can't let go and you can't hold on,
you can't go back and you can't stand still-
if the thunder don't get you then the lightning will!

-Robert Hunter



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