Greetings, Alan!
I guess, that micro-organisms are not used in the production of EPO
because they are not able to glycosylate the protein. Glycosylation is
important for the bilogical activity. At our university, transgenic
animals (mice, rabbits & cows) carrying the EPO-gene have been
produced. If I remember correctly, the first EPO-trasgenic animals
(sheep) were produced in Scotland.
Jukka Häyrinen
University of Kuopio/ Dpt. Biochemistry and Biotechnology
P.O.B. 1627
FIN-70211 KUOPIO
FINLAND
Tel. +358 71 16 3059, +358 40 515 0819
Fax. +358 71 281 1510
E-mail hayrinen at messi.uku.fi
WWW URL: http://www.uku.fi/~hayrinen/index.html
