IUBio

Pre-CTLs (fwd)

Darren J Forcier forcierd at GORT.CANISIUS.EDU
Wed May 7 11:05:26 EST 1997


Does anyone know the signal for "pre-CTL" cells to become a 
fully functionable cytolytic CTL cell???

Pre-CTL cells are cells that have already been committed to the CTL cell 
line.  However, they do not yet have cytolytic capabilities.  I'm 
wondering what the signal is for them to be fully differentiated and 
fully functionable.  I think that the explonation is probably the 
immunology catch-all "cytokine interaction," but if so, does anyone know 
what kind of cytokines and from what kind of T cells they come from?

Darren Forcier
forcierd at gort.canisius.edu

P.S.- This is not a question on an exam or for a  paper, but rather a 
burning question which has been in my head while taking an upper division 
immunology course.  We (the class) have been given the opportunity to 
pose these questions to a chatline.  I apoligize if we have been 
"bombarding" your chatline with questions, but I'm sure if there are any 
questions we could help anyone with, either now or in the future when we 
become successful biologists, we'd be more than happy to help you.

To Mr.Jeffrey Jackson - Thank you for your help and I'm sure that 
everyone, including our professor, is flattered by your compliment that 
we all sound like TAs with our intelligent burning questions.  Canisius 
College has an outstanding biology department and it is this kind of 
critical thinking and problem solving skills, that make our graduates 
successful scientists. 




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