In article <Pine.SOL.3.91.970507120516.8616B-100000 at gort.canisius.edu>
Darren J Forcier, forcierd at GORT.CANISIUS.EDU writes:
>Pre-CTL cells are cells that have already been committed to the CTL cell
>line. However, they do not yet have cytolytic capabilities. I'm
>wondering what the signal is for them to be fully differentiated and
>fully functionable. I think that the explonation is probably the
>immunology catch-all "cytokine interaction," but if so, does anyone know
>what kind of cytokines and from what kind of T cells they come from?
If by CTL you mean CD8+CD3+ T cell and by pre-CTL you mean naive CD8 T
cell than my question to you is: What is the signal for a naive CD4 T
cell???