IUBio

IL-1a Knockout

F. Frank LeFever flefever at ix.netcom.com
Sun May 25 20:43:54 EST 1997


In <5F77E385A8E at prl.pulmonary.ubc.ca> CDong at PRL.PULMONARY.UBC.CA
("Chunming Dong") writes: 
>
>Hello there:
>
>I am looking for a IL-1a deficient cell line or a IL-1a knockout 
>mouse model.  Any information should be highly appreciated!
>
>Chunming

Don't know, but want to tack on my renewed quest for info about
different molecular weight IL-1 fragments--e.g. 5kD, 17kD, 30kD?

If you don't know, someone knowledgeable about IL-1 knockouts might,
and might find my query here!

Different controls for different fragments? different effects?
individual differences (e.g. genetic) in proportions produced,
released? cleavage mechanisms? different parameters of induction? etc.,
etc.

F. Frank LeFever, Ph.D.          FAX usa (914) 947-3350
Helen Hayes Hospital
West Haverstraw, NY 10993



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