IUBio

IL-1a Knockout

F. Frank LeFever flefever at ix.netcom.com
Tue May 27 21:35:29 EST 1997


Yes, thanks--in the ball park.  Not so near to now as I'd like, and not
at the level I can handle (physiological rather than structural
chemical)), but if not in Dinarello's (1984?) or Nieto-Sampedro's
(1987?) references, could be a useful additional lead--e.g. for search
via Science Citation Index (to locate later articles citing it).

Thanks again!

Frank




In <338AFF30.32C2 at cas.org> Jeffrey Smoot <jsmoot at cas.org> writes: 
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>F. Frank LeFever wrote:
>>
>> 
>> Don't know, but want to tack on my renewed quest for info about
>> different molecular weight IL-1 fragments--e.g. 5kD, 17kD, 30kD?
>> 
>> If you don't know, someone knowledgeable about IL-1 knockouts might,
>> and might find my query here!
>> 
>> Different controls for different fragments? different effects?
>> individual differences (e.g. genetic) in proportions produced,
>> released? cleavage mechanisms? different parameters of induction?
etc.,
>> etc.
>> 
>> F. Frank LeFever, Ph.D.          FAX usa (914) 947-3350
>> Helen Hayes Hospital
>> West Haverstraw, NY 10993
>
>
>Is this in the ballpark of what you're after?
>-- 
>Jeffrey Smoot  (jsmoot at cas.org)
>614-447-3600 X3198
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>TI   Partial characterization of the high and low molecular weight
forms
>     of P388D1-derived interleukin 1
>
>AU   Prestidge, R. L.; Koopman, W. J.; Bennett, J. C.
>
>CS   Dep. Med., Univ. Alabama, Birmingham, AL, 35294, USA
>
>SO   J. Cell. Biochem. (1984), 26(2), 65-73
>
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