Hello everyone,
I am pretty confuse here about the route of immunisation!!! I am
currently working with a mouse model where I take my protein antigen in
Freund's adjuvant.... and immunised the victim via intraperitoneal route
.... in the hope of stimulating a good systemic response as well as good
T-cells reponse....
However, I have been receiving advice from people (immunologists)
and found that ip. immunisation is not a good way to go about if I want
a good systemic/T-cells reponse..... They all recommended subcutaneous
injection or intradermal injection....
Problem is I am so used to ip. route immunisation and my work have
been sort of based on ip. immunisation.... and things have not been
working very well for me... and on the other hand, if I change the route
of immunisation.. then my work is sort of down the drain!!!!
Does anyone have any insight to this!!!!????? Please!!!??
Thank you!!!!
Sincerely,
Grace Ho PhD student
Curtin University of Technology
Western Australia
Email: EHO17 at alpha1.curtin.edu.au