Expression of HLA Class II along with co-stimulatory molecules (e.g B-7)
has be shown to allow T cells to act as effective APCs. Activated T cells
can capture, process and present Ag to Class II-restricted T cells. This
capacity correlates with the synthesis of Class II. For further information
please refer to:
Barnaba V, Watts C, de Boer M , Lane P and Lanzavecchia A (1994)
Professional presentation of antigen by activated human T cells.
Eur. J. Immunol., Vol.24:p.71-75