In article <35A5C7A3.395E at LMB.RUG.AC.BE>, Tino Hochepied
<tino at LMB.RUG.AC.BE> wrote:
> Is it possible to target genes by means of homologous recombination in
> tissue culture lines, like e.g. hek293T ?
Yes it is very much possible. As evidence look up the work done by Jeff
Ravetch where he targeted SHIP in chicken DT3 cell lines. I think this
work is published in cell.
Kalpit