IUBio

auto-immune disease

awalley at radius.jr2.ox.ac.uk awalley at radius.jr2.ox.ac.uk
Fri Jun 12 03:37:05 EST 1998



James McNulty wrote:

> In article <6lh35e$6bo$2 at tempo.univ-lyon1.fr>, ribaux at physio.univ-lyon1.fr
> wrote:
>
> > I would like to know if does exist an auto-immune disease for sodium
> channels.
> > Please, send me a mail if you can help me (or if you know someone who can).
> > Thank you.
>
> I was told of a gene transfection experiment involving transfection of
> adenoviral-CFTR into lung epithelia of cystic fibrosis patients, where an
> autoimmune reaction against the (new) CFTR protein was observed. However,
> I have no idea if it was published or not, and I cannot remember who
> lectured me on the topic. Sorry.
>
> Ta, James

The only problem with this is that CFTR is a Chloride channel not a sodium
channel.

Andrew





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