IUBio

PHA action mode help

govind_pgi at yahoo.com govind_pgi at yahoo.com
Wed Oct 7 06:37:43 EST 1998


In article <6velhs$pr2$1 at nnrp1.dejanews.com>,
  strider at comteco.entelnet.bo wrote:
> Hello, can anybody tell me how the PHA works in the PBMC?
> I'm in Bolivia, and it's close to imposible for me to use
>  such tools as medline...
>
> Thanx 4 your help
>
> Cristina Alonso-Vega

 Hello there,

PHA is a lectin, means it binds to some sugar residues. Most probably it
binds some sugar residues attached to certain molecules on T cells and it
cross links those molecules. This transduces activation signals to T cells.
The important point is that presence of antigen presenting cells is
important.

This is as for as I know. Good luck

Govind
>
> ps please send me e-mail
>
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