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"AIDS Treatment News" online * New Issue #302 (searchable/indexed)

Carlton Hogan carlton at walleye.ccbr.umn.edu
Mon Oct 12 12:33:32 EST 1998


In article <6vqhr5$kc5 at dfw-ixnews5.ix.netcom.com>,
George M. Carter <gmc0 at ix.netcom.com> wrote:
>johnburgin at worldnet.att.net wrote:
>
>>>In any event, speaking of dementia, it was your idiotic statement that
>>>people now were taking LESS than the former commonly prescribed dose.
>
>>I gave you a study, I can give you others, ergo, it wasn't idiotic.

However, this study does not in any way reflect prescribing practices
today. Most physcians who are not HIV specialists (who may not know 
that dosages of 600 mg/day are clinically equivalent) probably go
to treatment guidelines. For example

Carpenter CJ, Fischl MA, Hammer SM, Hirsch MS et al "Antiretroviral 
therapy  for HIV infection in 1997; updated reccomendations of the 
international AIDS society-USA panel" 1997 JAMA:277 1969

Bartlett JG, Fauci AS et al "Guidelines for the use of antiretroviral 
agents in HIV-infected adults and adolescents" (developed by the panel
on clinical practices for treatment of HIV infection convened by the US 
DHHS and the Henry J Kaiser family foundation) Widely disseminated
included in 1997 MMWR, and most reference texts after 1997.

If some GP somewhere is just flying by the seat of his/her pants,
and does not refer to the guidelines, it is probable that they would 
at least read the package insert, which also recommends 600 mg.

Can you provide _any_ references that _anybody_ besides persons with 
HIV encephalopathy are being prescribed higher doses?

Next...

Carlton




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