IUBio

tolerance induction in mice

Christiane Hollmann chollmann at fz-borstel.de
Thu Oct 22 07:57:30 EST 1998


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Hallo everybody,

I just discovered this discussion forum and I am delighted about the
tolerance discussion. I am a newcomer in the tolerance field hoping that
someone knows an answer to my questions. 
Is it true that B cell tolerance can be induced by immunizing mice with
haptens whereas immunizing with peptides doesnot affect the B cell
system? Peptides are meant to induce T cell tolerance but there must be
some influence on the B cells via the CD4+ T cells. 
Does anybody know some literature or is experienced in this fields?
Thank´s for any help!

Christiane Hollmann
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