IUBio

dendritic cell lineage

Bruce Smith Bruce.Smith at Mail.TJU.Edu
Wed Aug 25 03:49:53 EST 1999



Gordon MacPherson wrote:

> James Good wrote:
>
> > To what extent are Langerhans cells and follicular dendritic cells of the
> > same developmental lineage?
>
> All the evidence is that they are completely distinct lineages.  There are
> dendritic cells in germinal centres (Grouard et al., Nature), but these are
> quite different from follicular DC.
>
> Gordon

But when?
Clearly, they are both myloid, but i'm not sure when the change occurs
there was a recent paper in JI when a group isolated three separate cell-types
based on phenotype
Ito vol 163 p 1409 99 august 1





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