Well Tyson, it kind of depends on what system you are asking about. I
assume you are asking about memory T cells that have been polarized to a
Th1 (inflamitory response- IFN-g, IL-2, and TNF-b) vs Th2 (IL-4, IL-10,
IL-5) response. The length of memory cell survival was already
referenced by preious respondents. As far as the effect of polarized T
cell responses, there are some excellent reviews published by A. Abbas
(nature, 96) and A. O'Garra: "Tcell subsets in autoimmunity" (Immunity?
97) on these subjects
IdGrad
Tyson wrote:
> Could anyone shed some light on what the effects of type 1 or 2
> polarisation of MEMORY T cells (either Tcm or Tem) would be on the
> maintenance of immunological memory?
>> ....papers on this topic are few and far between!
>> Thanks in advance,
>> Tyson
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