IUBio

linear differentiation of T cells

fred fredshaw at primenet.com
Tue Dec 28 12:42:10 EST 1999


On Thu, 09 Dec 1999 23:07:19 GMT, in
<HCW34.123671$V4.1621893 at news2.rdc1.on.home.com> "Tyson"
<tyson at canada.com> wrote:

>...would appreciate it if anyone could comment on whether or not my diagram
>(a 25.6kb jpeg attachment on this message) is correct or at least makes
>sense.
>
>Thanks,
>
>Tyson

The linear model is nice, but it cannot account for the
reversion of memory cells to naive cells, which was one
of the more recent discoveries arising from HIV research
into the protease inhibitor drugs which trap T cells in
the blood compartment (through interference with adhesion
molecules) where no immune challenge is found, thus the 
cells reverted to naive cells (infected memory cells, by
the way, which blew away all the initial excitement about 
"immune reconstitution" through cancer chemotherapy-based
"antiretrovirals" <pure fucking insanity> !).

fred





More information about the Immuno mailing list

Send comments to us at biosci-help [At] net.bio.net