Dixit, Bharat L. wrote:
>> does any one knwos about a software or some method which can
> tell the imunogenic(antigenic) areas in a protein.
See:
Vaccine 1998 Nov;16(19):1880-4
Prediction of well-conserved HIV-1 ligands using a matrix-based
algorithm, EpiMatrix.
Schafer JR, Jesdale BM, George JA, Kouttab NM, De Groot AS
But it is more about CTL epitopes than B-cell antibody
response prediction.
The GCG software has an "antigenicity" index as part of proetin
sequence analysis in PEPTIDESTRUCTURE. I'm not sure
if it has been empirically tested. The method used by GCG
was published in: Jameson and Wolf (CABIOS, 4(1); 181-186
(1988)
--
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|Brian T. Foley btf at t10.lanl.gov |
|HIV Database (505) 665-1970 |
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