IUBio

Selenium & Cancer

mark mark.haynes at mail.tju.edu
Fri Jul 2 12:18:12 EST 1999


Ralph L. Samson wrote:
> 
> I recently read about the big new study of the effect of Selenium
>  This was prompted by the
> results from an earlier study that was looking for a benefit for skin
> cancer.  It turned out there was no benefit for skin cancer but 
> benefits for many other cancers.  This was puzzling since the benefit from
> selenium in supplying the antioxidant glutathione peroxidase should affect
> all cancers.

Please explain.  are you saying that selenium turns on a glutathione pathway 
or is it a co-factor for the enzyme?



> Another study, by Will Taylor at the University of Georgia
> School of Pharmacy, showed that selenium prevented the spread of HIV from
> infected cells.  This suggests that a similar mechanism might be involved
> with cancer.

Only cancers that are caused by a retrovirus, i would assume, since cancer 
doesn't spread to other cells like an infection.

> That is, selenium in a cancerous cell might block the spread
> of the cancer to other cells.  Thus, it would not be truly prevention or
> a cure, but limiting cancer to a very small region might be almost as good.
> But what about the skin?

what affects are there on warts?

Markh



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