At 12:05 20/05/99 +0200, you wrote:
>Do there exist cellmarkers specific for neutrophils ? (not eosinophils,
>monocytes, macrophages, .....). Antibodies or maybey a technique based on
>their enzyms in the granules (besides peroxidase) ?
>>isabel.desmet at rug.ac.be>>>Dear Colleague,
There is a lot of surface antigens which can be used for identifying
neutrophils, in addition to classical enzymes markers. See for example:
KUIJPERS et al. Membrane surface antigen expression on neutrophils.
Blood, 1994, 78: 1105-1111.
For example in immunohistochemistry (on 'classic' paraffin blocks), we can
easely identify them with the anti-elastase (NP57 Mab from Dako)..
Best of luck with your research.
Sincerely - Philippe Esterre
International network of Pasteur Institutes
-------------------------------------------
Philippe ESTERRE (DVM, PhD, MSc)
Head of Immunology Unit
Institut de Recherches Médicales L. Malardé
BP 30 - 98713 / Papeete - Tahiti - French Polynesia
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Fax: 689 43 15 90 E-mail: esterre at malarde.pf
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