1-10% T cells can directly recognize the alloantigen, which is not
self-MHC restricted. It seems to be controversial to the classical T
cell recognition model of self-MHC restricted
One explanation is that allo-MHC molecule mimic the structure of
self-MHC and peptide complex. Is there any experiment verify this
hypothesis?
I would like to discuss with you.
Thank you for your consideration
