IUBio

THE FAUCI FILES, 3( 43): Dr. Clerici Responds to The Failed ART Rationale

Charles P. McCarthy, P.M.D. (Hon) Pandoc at jps.net
Wed Apr 5 02:12:27 EST 2000


W. Fred Shaw wrote:

[edit]

> W. Fred Shaw, Editor

Nice, Fred.  Sounds like a vocation...

[edit]

>   From AIDS (Clerici et al, 1/28/00):
> 
>      "We wanted to show that, despite being highly
>       effective on reducing HIV viral load, HAART
>       does not necessarily augment the immune response."
> 
>   Response to Clerici: Yes, but the scientific rationale for
>       using HAART was to reconstitute the immune response by
>       decreasing viral load thus allowing CD4s to increase
>       and be potent weapons--once again--against HIV and
>       other pathogens..
> 
>   Answer from Clerici: "... this is exactly the point; you got
>       exactly at the core of the matter: the assumption that the
>       immune system would automatically have been reconstituted
>       once that the virus is suppressed by HAART does not
>       hold true."

Gee, I guess cell-to-cell transmission of viral genomic 
material, copious secretion of soluble viral glycoprotein
after numerous viral passages at the expense of infectious
virion production, and the pathogenic totapotency of gp120 
continues despite advanced "editorial" rhetoric, and demonstrable
decreases of peripheral viral load.

"Life is a membrane that reproduces."
                        Pandoc




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