In article <ant0416230b0Pk=+ at mrc7acorn1.path.cam.ac.uk>, Mike Clark
<URL:mailto:mrc7 at cam.ac.uk> wrote:
[snip]
> In text books and papers you frequently read that monoclonal antibodies
> usually have affinities of 100 mM or above.
^^^^^
[snip]
Whoops there goes a classic mistake in mixing ideas of association and
dissociation constants!
should have been 'have affinities [measured with dissociation constants] of
100mM or below'
Mike <URL:http://www.path.cam.ac.uk/~mrc7/>
--
o/ \\ // || ,_ o M.R. Clark, PhD. Division of Immunology
<\__,\\ // __o || / /\, Cambridge University, Dept. Pathology
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