Yes because of 1) the plethora of cytokines/ interlukins/ and various others endocrine
signals present in vivo @) NK cells will attack anything that has the appropriate cell
surface antigenic markers (HLA or MHC) which alot detection when activated. It dosn't
descriminate.
maciej simm wrote:
> got a reference? NK's are one of my particular interests these days.
> thanks,
>> Maciej
>> HHarada wrote:
>> > Somebody, tell me about meaning of interaction of DC and NK cells in vivo.
> >
> > Recently, it has been reported that NK cells recognize and kill autologous
> > dendritic cells in vitro. Authors in a paper describe
> > that the interaction induce increase of killing activity and IFN-g
> > production. However, my question is why NK cells kill such a useful cells in
> > vitro.
> > Does this phenomenon occur in vivo actually ?
> >
> > Please, somebody help me.
> >
> > Hideki Harada