IUBio

Dendritic cells and NK cells

Doc 2 b bifero at earthlink.net
Tue Feb 8 21:02:32 EST 2000



Network Services Kit User wrote:

> Yes because of 1) the plethora of cytokines/ interlukins/ and various others endocrine
> signals present in vivo @) NK cells will attack anything that has the appropriate cell
> surface antigenic markers (HLA or MHC) which alot detection when activated.  It dosn't
> descriminate.
>
> maciej simm wrote:
>
> > got a reference? NK's are one of my particular interests these days.
> > thanks,
> >
> > Maciej
> >
> > HHarada wrote:
> >
> > > Somebody, tell me about meaning of interaction of DC and NK cells in vivo.
> > >
> > > Recently, it has been reported that NK cells recognize and kill autologous
> > > dendritic cells in vitro. Authors in a paper describe
> > > that the interaction induce increase of killing activity and IFN-g 
> > > production. However, my question is why NK cells kill such a useful cells in
> > > vitro.
> > > Does this phenomenon occur in vivo actually ?
> > >
> > > Please, somebody help me.
> > >
> > > Hideki Harada





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