Ranga Uday Kumar wrote:
>> Dear netters,
> Any one knows if there is a T-cell line that expresses
> both CD4 and CCR5? Thank you for the help.
Short answer: I was under the impression that
most T-cell lines express CD4 and CXCR4, and that macrophages
and other lines express CD4 and CCR5, but I could be wrong.
I know that people have made cells which express
CD4 and CCR5 and not CXCR4, for purposes of findng ot which
co-receptor (CCR5 or CXCR4) a given isolate uses.
I can't find such cell lines available from the AIDS
Reagent Repository: http://www.aidsreagent.org/
I think your best bet is to find authors who
have reported using such lines (search MedLine for
"Imunodeficiency and co-receptor and CCR5" for
example) and asking them where they got their cells.
>> --
> ________________________________________________________
> Ranga Uday Kumar Ph.D.
> Faculty Fellow
> Molecular Biology and Genetics Unit
> Jawaharlal Nehru Center for Advanced Scientific Research
> Jakkur Post, Bangalore 560 064
> India
> Tel: +91 (80) 846 2750 Ext. 241
> Fax: +91 (80) 846 2766
> ________________________________________________________
>> ---
