IUBio

Ascites in Rabbits?

juniorgator99 at aol.com juniorgator99 at aol.com
Tue Sep 12 16:31:48 EST 2000


I have developed a rabbit-rabbit  (rabbit plasmacytoma cell line fused
with rabbit splenocytes) monoclonal antibody and wanted to know if you
can produce ascites in rabbits practically?

I know ascites production is routintely done in mice, but has anyone
heard of it done in rabbits?  If so what cell dosage would be needed to
inject, any ideas of yield, and any other pros and cons that go along
with this type of procedure?

Also what about injection of a rabbit monoclonal into nude mice for
ascites production?

Thanks for your help..

Junior


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