IUBio

Definition of a cellular signal

Mark Haynes Mark.Haynes at Mail.TJU.Edu
Tue Sep 19 12:49:21 EST 2000


Yo mismo n' moi aussi.
I was thinking of signalling from the biochemical angle and not really the
reciever angle.  From the example Jay gave, to me the signal is the binding of
the cytokine to the receptor --  in a vacuum.  by that i mean that its not
necessary for the recieving cell to respond.  cytokine binds to a extracellular
receptor and a chain of events happens -- protein shape change, ion flux,
kinase/phosphatase activity and the like.

Jay Mone wrote:

> My definition of a cellular signal is any substance or process which occurs
> between two cells  which results in a specific cellular response from one of
> the cells.  For example, the release of a cytokine by one cell, which is
> taken up by a second cell, resulting in a specific response from the second
> cell.  I don't know if I've ever seen the term defined.  I'd be interested
> to know.
>
> Jay Mone'
>
> ---






More information about the Immuno mailing list

Send comments to us at biosci-help [At] net.bio.net