IUBio

Definition of a cellular signal

Vladimir Matveev vm_spb at my-deja.com
Wed Sep 20 00:33:03 EST 2000


According to you, "a signal is the binding of the cytokine to the
receptor". This definition is extremely limited. A cell has many other
kind of signals.

***
In article <39C7A721.F373B041 at Mail.TJU.Edu>,
  Mark Haynes <Mark.Haynes at Mail.TJU.Edu> wrote:
> Yo mismo n' moi aussi.
> I was thinking of signalling from the biochemical angle and not
really the
> reciever angle.  From the example Jay gave, to me the signal is the
binding of
> the cytokine to the receptor --  in a vacuum.  by that i mean that
its not
> necessary for the recieving cell to respond.  cytokine binds to a
extracellular
> receptor and a chain of events happens -- protein shape change, ion
flux,
> kinase/phosphatase activity and the like.
>
> Jay Mone wrote:
>
> > My definition of a cellular signal is any substance or process
which occurs
> > between two cells  which results in a specific cellular response
from one of
> > the cells.  For example, the release of a cytokine by one cell,
which is
> > taken up by a second cell, resulting in a specific response from
the second
> > cell.  I don't know if I've ever seen the term defined.  I'd be
interested
> > to know.
> >
> > Jay Mone'
> >
> > ---
>
>


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