IUBio

www prediction of promiscuous class I MHC and proteosomal cleavage fragments

Harpreet Singh hsingh at imtech.res.in
Wed Apr 10 23:17:49 EST 2002


Dear all,

If you are looking for an on-line epitope prediction tool, please
check the following URLs.

1) http://www.imtech.res.in/raghava/propred1/

A matrix based prediction server, available for 47 class-I MHC
alleles. The server also provides options for simultanous filteration
of proteasomal and immunoproteasomal cleavable fragments. The
graphical, tabular, and colored text display options will ease the
indentification of promiscuous or allele specific cytotoxic fragments.

2) http://www.imtech.res.in/raghava/propred/

A matrix based prediction server, available for 51 HLA-DR alleles. The
different result display options will ease the identification of
hepler epitopes
The server implements matrices taken for Struniolo et al., 1999. A
windows application TEPITOPE also uses same matrices, however it is
available for 25 alleles.

The users can also download the matrices

Please feel free to comment on any aspect.

Harpreet Singh
Research Officer,
Indian Council of Medical Research,
New Delhi.




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