"Gordon MacPherson" <gordon.macpherson at path.ox.ac.uk> wrote in message
news:3E01CC45.E7283C21 at path.ox.ac.uk...
> DC are continually entering tissues as precursors from the blood. In most
> tissues e.g. respiratory tract, gut, they spend only a few days before
migrating
> via lymph to draining nodes. Despite what many athorities suggest, they
do this
> continually in the absence of any inflammatory or "danger" stimulus. They
are
> continually transporting self Ag for presentation to T cells and this very
> probably plays an importan part in self tolerance.
>> Gordon MacPherson
>
This is really very interesting! Do macrophages also present self-Ag to Th
cells?
Dan
