for IL-1 it is the pro-protein that is secreted and then ICE cleaves . I
could be wrong though
"Denis Gaucher" <dgauch at po-box.mcgill.ca> wrote in message
news:3C71E506.EDDBAF6A at po-box.mcgill.ca...
> Hi!
>> Does anybody here know how IL-1B and IL-18 get secreted out of the cell
once they are converted to
> their mature form by caspase-1?? Every single article I have read so far
about activation of these
> cytokines seems to avoid the question.... How do they get secreted if
they don't contain a
> secretion signal sequence??
>> Thanks for your help!
>> Denis
