IUBio

[Immunology] PhD Candidate Trying to make an Immunoconjugate

DarkProtoman Protoman2050 at gmail.com
Fri Aug 18 01:29:32 EST 2006


Hey all, I'm a immunology PhD candidate, and I'm testing a cancer
therapy in mice for my dissertation. How would I make a
immunoconjugate's payload be part of the antibody itself, instead of
being merely "glued" on? The reason is b/c I'm using sodium
fluoroacetate as the payload, and I don't want it to fall off the
antibody, wreaking all sorts of catastrophic effects. Poor mousey... I
think I have to use genetic engineering, but after that, I'm lost. Any
help here? Thanks!!!!! If you tell me how, I'll list you in the credits
section!



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