In article <BILL.94Nov28150159 at cortex.nsma.arizona.edu>, bill at nsma.arizona.edu (Bill Skaggs) writes:
|>|> Fortunately for all of us doing compartmental modeling, Michael Hines
|> worked out, a few years back, an efficient implicit integration method
|> for tree structures. It's stable and first order in the number of
|> compartments -- altogether very nice. It is incorporated in his
|> Neuron simulator and several other biophysically realistic simulators,
|> and is described in the paper, "Efficient computation of branched
|> nerve equations", M. Hines, Int J Bio-Med Comp 15:69-76 (1984).
|>
The original posting mentioned an implementation of dendro-dendritic
synapses. You might also take a look at the GENESIS simulator, which has
the Hines method as an option, and also has a dendro-dendritic synapse as
one of the basic simulation components. (For information on GENESIS, you
can email genesis at cns.caltech.edu.)
Dave Beeman
