Hi, everyone,
it's me again who is doing some modeling work about NO transmission.
questions:
1. If increasing the concentration of glutamate, what will be caused
in its receptor channel (NMDA or non-NMDA) current.
For example:
2-fold increase in the concentration of glutamate release will cause:
(a) 2-fold increase in the current of *single* receptor channel?
or
(b) 2-fold increase in the number of open channel?
or
(c) some other changes?
2. If the concentration of glutamate has a fast change, for example,
the glutamate concentration is changed only for 2 ms, or even less,
this kind of transient change will also cause some change in its receptor
channel current?
Any reply will be highly appreciated !
