In article <3dl8p3$l7q at newsbf02.news.aol.com>, rvallen at aol.com (RVAllen) writes:
> I am writing a paper for school on the phenomenon of Phineas Gage and I
> was wondering if anyone knows exactly WHERE the brain damage occurred and
> what areas were responsible for his behavioral deficits. What is the area
> in a human brain that corresponds to area 46 of a monkey? I have found a
> few articles attributing similar deficits in monkeys to lesions of the
> principle sulcus and area 46, but I am having trouble associating these
> areas with Gage's brain. Thank you so much for your help!
>> Princeton University student on break and confused.
The homolog to monkey area 46 is the dorsolateral prefrontal cortex; you might
look for work by Patricia Goldman-Rakic at Yale, for starters. Its role in
the control of volitional eye movements has been extensively explored; a good
place to start on that literature would be papers by Charles Pierrot-
Deseilligny. Happy hunting!
Larry Abel
Dep't of Ophthalmology
Indiana University
