IUBio

Help! Confused Neuro student....

siwek at acs.bu.edu siwek at acs.bu.edu
Thu Dec 29 18:34:38 EST 1994



> 
> I was wondering if anyone would please answer the following question:  Do
> humans have a principal sulcus?  If not, what area of the frontal lobe
> (particularly prefrontal cortex) corresponds to the principal sulcus and
> area 46 of monkeys?  I am researching the behavioral deficits of EVR and
> Phineas Gage, and I am trying to explain "normal" prefrontal patients and
> their memory deficits in juxtaposition to the behavioral deficits that
> these two patients show.....
> 
> Thanks so much for your help!
> Cognitive Neuro student on vacation and away from school!

I do not believe that the human brain has a specifically designated principal 
sulcus, however there is an area 46.  The real issue is whether the areas are 
homologous.  This issue is unresolved.  My colleague Dr. Pandya is presently 
working on the issue of macaque/human prefrontal cortical homologies and I will 
be pleased to ask him in january to render an opinion.  In the meantime try "The 
frontal Lobes" by Stuss and Benson.  May be of some help in your quest.  For 
further discussion E-Mail me.  Good luck




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