In article <jdbecker-241194150332 at sainsbury.psych.ucalgary.ca>, jdbecker at acs.ucalgary.ca (Jason Becker) says:
>>Does anyone know the name of endogenous PCP (phencyclidine)? I think it was
>discovered by looking at pig brains.
"Alpha-endopsychosin" is probably the relevant stuff!:
Contreras-PC; DiMaggio-DA; O'Donohue-TL (1985) Evidence for an endogenous peptide
ligand and antagonist for PCP receptors. Prog-Clin-Biol-Res. 192: 495-8
"Alpha-Endopsychosin, an endogenous ligand for the phencyclidine receptor, has been
isolated from porcine brain. The endogenous ligand is a peptide and has similar actions to
PCP and is selectively distributed in the brain. A PCP analogue, Metaphit, has also been
found to be an effective PCP antagonist. This antagonist may be useful for evaluating the role
of the brain's alpha-endopsychosin system and may have a number of important clinical
uses."
