IUBio

Pallidotomy effects question

David Stout dstout at mail.nuc.ucla.edu
Thu Mar 2 17:52:48 EST 1995


I was surprised the Primetime show last night did not go into the possible
problems in greater detail. The area in question is very close to the
optic nerve and I recall problems with a few patients going blind in one
eye.

My question is, what are the effects of over-lesioning the pallidum.
Insufficient lesions will obviously leave some Parkinsonian symtoms, by
what if you destroy too many inhibitory nuerons? I don't believe it causes
motor problems, but I'm not sure. Also wondering about the behavioral
effects of mucking about with these seretonergic neurons.

Comments and answers appreciated, e-mail or public.
David Stout

-- 
 "Listen -- strange women lying in ponds distributing swords is no basis for a system of government.  Supreme executive power derives from a mandate from the masses, not from some farcical aquatic ceremony."   Dennis, Holy Grail



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