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Electrochemical Detection of Single molecules

x011 at Lehigh.EDU x011 at Lehigh.EDU
Mon Mar 27 08:46:17 EST 1995


Science 10 February 1995 - Electrochemical Detection of Single Molecules
by Fan & Bard page 871-874
Abstract:
"The electrochemical behavior of a single molecule can be observed by tapping
a small volume of a dilute solution of the electroactive species between an
ultramicroelectrode tip with a diameter of ~15 nanometers and a conductive
substrate.  ..cut ...  The response was stochastic, and anodic current peaks
were observed as the molecule moved into and out of the electrode-substrate
gap.  ...cut...."

This may have some value to neural science if the currents generated are
related to different neurotransmitters.  I keep thinking that neurotransmitters
may be transported to the synapses by the tuned electrical oscillations
of neural activity.  The above tool may answer this question.
Ron Blue




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