On Fri, 13 Oct 1995 12:43:33 +0100,
pierre <luppi at cimacpcu.univ-lyon1.fr > wrote:
>In article <453i80$rt8 at griffin.ccc.nottingham.ac.uk>,
>mzycnb09 at granby.nott.ac.uk (Arthur Vickers) wrote:
>>> Hi there!
>> If anyone knows of some good reviews/books with information on the
>> neurobiology of sleep they would be most helpful. In particular I'm looking
>> for information on the areas of the brain and pathways involved in control of
>> sleeping and waking, and in the neurotransmitter/receptor combinations that
>> are involved in these pathways. Thanks. :)
>> Arthur.
>>Have a look on our WWW neuroscience site : http://ura1195-6.univ-lyon1.fr/>You will find a lot of informations (with pictures) and Pr Jouvet's
>reviews concerning neurons, neurotransmitters, structures and their
>pathways directly involved in the generation of the different states of
>vigilance.
It's my understanding that there has been a fair amount of
controversy about the exact control mechanisms in the brain which are
involved in sleep. One basic review book is JA Hobson. "Sleep".
Scientific American Library, 1989.
I'm pretty sure I read somewhere recently about some new information
from Hobson, where he said that dopamine and norepinephrine fall in
sleep, and when REM sleep occurs, DA and NE fall close to zero and
acetylcholine shoots up. (There are various ascending neuromodulatory
pathways which arise out of nuclei in the recticular activating
system in the brain stem, and which appear among other things to
control brain states.)
AJR
