Hello all!!
I fully agree with Stephan Anagnostaras
advice of not taking melatonin unless you have nothing
better to do. I also agree with his rationale (except
that pineal melatonin. though engraining the cycling
of the remaining bodily production of melatonin, is
solely a tiny fraction of this indol -perhaps only one
thousand or less-; the greatest part is produced by
enterochromaffin tissue and by the remained lumicaptor
ectoderm).
However, I should mention here that my
boss took twelve grams of melatonin in three weeks,
before inchoating our melatonin-modulated IL-2 immuno-
therapeutic adjuvancy in resected exocrine pancreatic
adenocarcinomae. (See under Paolo Lissoni in Medline
for achieving a good description of the field). Though
I dare not to ascertain it :-), he says he did not became
impotent nor had any other trouble. We now have three pa-
tients, having about 20,000 to 25,000 times the body pro-
duction of melatonin administered daily per os (40 mg),
alive (two of them still free of symptoms) two years after
their Whipples; however, we also supplemented them as per Kal-
ser & Ellemberg (1985), chemitherapy as per D. Bronn
et al. (# 448 in ASCO Proc. vol 14, March 1995, p. 193),
antioxidants and, regarding depression, diagnosis conceal-
ing due to prognosis notoriety. We obtain our melatonin
from the same source (in Europe) that Dr. Lissoni (see
Medline); Sigma's, up to my knowledge, is not for human use.
These are among the good reasons to take MLT;
lacking them, I think Stephan's advice is a sage one.
Cheers,
Mariela
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Prof. Mariela Szirko,
<postmaster at neubio.sld.ar>
Centro de Investig. Neurobiologicas, Ministry
of Health & Welfare, Argentine Republic; and Lab. of
Electroneurobiological Res., Hospital "Dr. Jose Tiburcio Borda",
Municipality of Buenos Aires,
Office: Phone/Fax (54 1) 306 -7314
e-mail <postmaster at neubio.gov.ar>
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