Dag Stenberg (stenberg at cc.Helsinki.FI) wrote:
} Dan Komaromi (komaromi at ucla.edu) wrote:
} } In my brief introduction to melatonin, I've heard reports that it
} } stimulates growth hormone. Would this allow for any growth after an
} } organism's normal growth period, or simply increase the growth rate
} } during this period?
I addition to the studies I cited in my other message, there is a cell
culture study of the effects of melatonin (MEL) on tumor cell growth.
While prolactin and growth hormone increase tumor growth, MEL at
physiological tissue concentrations was able to block these effects,
although it had no influence on tumor growth when used alone
(Lemus-Wilson &al., Brit.J.Cancer 72:1435-1440, 1995). The conclusion
was that the previously reported oncostatic activity of MEL could be
linked with an antagonism of the mitogenic activity of, especially,
prolactin.
Dag Stenberg
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Dag Stenberg MD PhD stenberg at cc.helsinki.fi
Institute of Biomedicine tel: int.+358-0-1918532
Department of Physiology fax: int.+358-0-1918681
P.O.Box 9 (Siltavuorenpenger 20 J) tlx: 1002125 finuh sf
FIN-00014 University of Helsinki,Finland
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