Captopril:Induction of Emotionnal Indifference by Captopril
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Captopril is an angiotensin converting enzyme(ACE)inhibitor which has been reported to
have "anti-depressant" effects.In fact,the alleged anti-depressant effect of captopril
and related molecules is a pseudo-anti-depressant effect because captopril is,in
fact,a potent thymoanesthesiser! A thymoanesthesiser is a molecule which induces
pharmacological blunting of emotions.Thymoanesthesisers induce emotionnal indifference
reminiscent of the blunting of affect which is seen in the negative forms of schizophr
enia.
There are many thymoanesthesisers wrongly classified as "anti-depressants"! For
instance:
I.The serotonin re-uptake blockers such as fluvoxamine,paroxetine,citalopram,etc.
2.Maprotiline.
As psychopharmacologists have only experimented their products on animals and
others(!)they have misinterpreted thymoanesthesy as an "anti-depressant" effect
because the patients who are emotionnally anesthesised do not complain anymore of
being depressed!!! So these people wrongly misinterpret emotionnal indifference as an
"anti-depressant" effect.This error is similar to the case of a person who would
suffer from painful hemorhoids and who would stop complaining when his doctor would
put Xylocaine(an a
nesthesic)on his hemorhoids! A naive doctor may then proclaim that his patient is
"cured" with Xylocaine as he or she does not complain anymore...The situation that we
have now with thymoanesthesisers is exactly similar but instead of anesthesing
physical pain you anesthesise psychological pain.Anesthesing psychological pain
is,clearly, NOT an anti-depressant effect as a true anti-depressant effect should
stimulate rewarding emotions and the desire to live,despite adverse conditions.A true
anti-depressan
t should not substract a part of your personality,as thymoanesthesisers do.
When experimenting with captoptil I noticed that this molecule would induce a quite
strong indifference to everything,sex included! Captopril can make you impotent
because it suppresses the DESIRE to engage in copulation.I would be interested to know
what is the real percentage of people taking ACE inhibitors who suffer,afterwards,of
impotence?
This impotence can be reversed by yohimbine.
What is interesting with captopril is that it can induce depression if you stop the
medication rather abruptly.This is a very interesting observation as normal
thymoanesthesisers do not induce depression when they are,abruptly,stopped.
The emotional indifference induced by captopril opens a new avenue of research in the
field of negative schizophrenia.
